Czech Society for Structural Biology
Česká společnost pro strukturní biologii



The Czech Society
for Structural Biology
(Česká společnost
pro strukturní biologii

Videnska 1083
CZ-142 20 Prague
Czech Republic

CSSB@structbio.org
VAT number: 0022869433
account num.: 2300076583/2010
IBAN: CZ2820100000002300076583
SWIFT/BIC: FIOBCZPPXXX

More information on the web pages of Richard Štefl

Afiliation:  CEITEC - Central European Institute of Technology, Masaryk University, Kamenice 5/A4, CZ-62500 Brno,

 Research Interests:

Protein-RNA and protein-protein interactions and their roles in the regulation of gene expression
Structural epigenetics
Integrated structural biology

Five selected papers

R. Stefl, F.C. Oberstrass, J L. Hood, M. Jourdan, M. Zimmermann, L. Skrisovska, C. Maris, L. Peng, C. Hofr, R.B. Emeson, F.H. Allain: The solution structure of the ADAR2 dsRBM-RNA complex reveals a sequence-specific read out of the minor groove. Cell 2010, 143(2) 225-237.
A. Tudek, O. Porrua, T. Kabzinski, M. Lidschreiber, K. Kubíček, A. Fořtová, F. Lacroute, Š. Vaňáčová, P. Cramer, R. Štefl, D. Libri: Molecular Basis for Coordinating Transcription Termination with Noncoding RNA Degradation. Mol Cell 2014, 55(3) 467-481.
V. Bačíková, J. Pasulka, K. Kubíček, R. Štefl: Structure and semi-sequence-specific RNA binding of Nrd1. Nucleic Acids Res. 2014, 42(12) 8024-8038.
O. Porrua, F. Hóbor, J. Boulay, K. Kubíček, Y. D’Aubenton-Carafa, R. K. Gudipati, R. Štefl, D. Libri: In vivo SELEX reveals novel sequence and structural determinants of Nrd1-Nab3-Sen1 dependent transcription termination. EMBO J. 2012, 31(19) 3935-3948.
K. Kubíček, H. Černá, P. Holub, J. Pasulka, D. Hroššová, F. Loehr, C. Hofr, Š. Vaňáčová, R. Štefl: Serine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1. Genes Dev. 2012, 26(17) 1891-1896.

Structures in PDB: 2M8H, 2MOW, 2M88, 2LTO, 2LO6, 2LLI, 2KVI, 2L41, 2L2J, 2L2K, 2L3C, 2L3J, 2FY1, 2B7T, 2B7V, 2ES5, 2ES6, 2ESE, 1YSV, 1RVH, 1RVI, 1PQT, 1KR8

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